...who was earlier?

Eddie Cantor - born Isadore Itzkowitz; 1892 - 1964

Buster Keaton - born James Frank Keaton; 1895 - 1961

Marty Feldman - 1933-1982; his striking eyes apparently came from nasty hyperthyroidism (Interestingly, "...buried in Forest Lawn Cemetery in Los Angeles, California near his idol, Buster Keaton, in the Garden of Heritage, lot 5420." from the Marty Feldman Home Page)

Barney Google - comic strip character, buddy of Snuffy Smith

Jerry Collonna - second banana to Bob Hope. I can't find dates for him easily. Not to be confused with Jerry Colona , who seems to be a trombonist