>Is the orphan of "orphan drug" related to the parentless definition of orphan? I can stretch the two definitions together, but I am interested in a more definitive answer.

I seem to be impaled on the horns of a virtual prisoner's dilemna: should I cooperate by posting my opinion as a "service" to Brandon, or should I answer with a flippant YCLIU? (there was the third option of remaining silent in hopes that an expert in pharmacology law, or even a legislator, would eventually wander along and post a definitive reply; but I've blown that one).

anyway, my theory is that orphan drugs are so-named because of the neglect and abandonment they received due to perceived unprofitability. that's my theory and I'm sticking to it.