MEANING: noun: A person having a bad reputation.
verb tr.: To defame: to attack the reputation or to disgrace.
adjective: Having a bad reputation.

ETYMOLOGY: From Latin in- (not) + fama (reputation). Earliest documented use: for noun: 1413; for adjective: 1551; for verb: 1413.

IN GAME - where a bridge player wants to end up

IN FLAME - how we might go down in the Army Air Corps

SINFAME - Ebenezer Scrooge, Casanova, Lizzie Borden had it