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Carpal Tunnel
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Carpal Tunnel
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In an article in the most recent issue of the Journal of the Amercian Medical Association, an article on the effect of Niacin as an HDL-raising drug in diabetic patients. The authors -- Doctors MB Elam, DB Hunninghake, KB Davis et al. -- conducted a double-blind study in which some patients received Niacin and others a placebo. Folks who take Niacin report a flushing sensation in the face, toes and fingers when they take this drug. The researchers were concerned that the absence of this flushing sensation would tip off the patients receiving the placebo, which would be a bad thing, from an experimenter's point of view. Their solution to this problem was reported as follows:
"Some of the niacin placebo tablets (15%) contained 50 mg of niacin to minimize unblinding of participants secondary to absence of flushing (a common adverse effect of niacin)."
"Unblinding"?
Is this what Jesus did for blind Bartimaeus the beggar on the road from Jericho? (Mark 10:46-52)
Is this really a word? Or just another example of Medspeak?
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Carpal Tunnel
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Carpal Tunnel
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Way to go, Marty! But--haven't you ever heard of 'window dressing'? 
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Carpal Tunnel
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Carpal Tunnel
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Usually only in regards to a young blond biddy attached to the arm of an older rich guy.
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Carpal Tunnel
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Carpal Tunnel
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The Merriam-Webster definition seems not to include the usage in the JAMA article.
The medical definition looks like the real thing, however.
I am now unblinded to this usage/meaning.
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Carpal Tunnel
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Carpal Tunnel
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Going off on a tangent here (a decidedly rare occurrence in this forum)...all this unblinded talk has reminded me of a song by Manfred Mann <blinded by the light>. Has ANYBODY ever figured out what on earth he is saying.
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enthusiast
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enthusiast
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a song by Manfred Mann <blinded by the light>. Has ANYBODY ever figured out what on earth he is saying.
No, I've got no bloody idea, bel, and I hope someone can enlighten us. I'm sure I'm suffering from a bad case of Mondegreen here. I've always thought the next line went:
Wrapped up like a douche another owner in the night
?????
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Carpal Tunnel
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Carpal Tunnel
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Blinded by the Light
Manfred Mann's Earth Band
- words and music by Bruce Springsteen
- Manfred Mann's Earth Band version (Warner 8252) was released August 1976
and reached #1 in early 1977. It was in the Billboard Top 40 for 15 weeks.
- lyrics as recorded by Manfred Mann's Earth Band on the 1976 album
"The Roaring Silence" (Warner 3055)
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
Madman drummers bummers, Indians in the summer with a teenage diplomat
In the dumps with the mumps as the adolescent pumps his way into his hat
With a boulder on my shoulder, feelin' kinda older, I tripped the merry-go-round
With this very unpleasin', sneezin' and wheezin, the calliope crashed to the ground
The calliope crashed to the ground
But she was...
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
Some silicone sister with a manager mister told me I go what it takes
She said "I'll turn you on sonny to something strong, play the song with the funky break"
And go-cart Mozart was checkin' out the weather chart to see if it was safe outside
And little Early-Pearly came by in his curly-wurly and asked me if I needed a ride
Asked me if I needed a ride
But she was...
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light
She got down but she never got tired
She's gonna make it through the night
She's gonna make it through the night
------ guitar solo ------
But mama, that's where the fun is
But mama, that's where the fun is
Mama always told me not to look into the eye's of the sun
But mama, that's where the fun is
Some brimstone baritone anticyclone rolling stone preacher from the east
Says, "Dethrone the dictaphone, hit it in it's funny bone, that's where they expect it least"
And some new-mown chaperone was standin' in the corner, watching the young girls dance
And some fresh-sown moonstone was messin' with his frozen zone, reminding him of romance
The calliope crashed to the ground
But she was...
Blinded by the light, revved up like a deuce, another runner in the night
Blinded by the light, revved up like a deuce, another runner in the night
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Carpal Tunnel
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Carpal Tunnel
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Regarding the second line, see http://www.straightdope.com/classics/a5_148.html
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old hand
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old hand
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An interesting thread Pattersteve (if I may make so bold with your name).
What ?I find fascinating about this is that they're trying out Niacin, in a double-blind experiment, against a placebo, that also contains Niacin. Is this one for the Ig Nobel Awards?
cheer
the sunshine warrior
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