I never found Python remotely humorous in HS.  There were a lot of smart guys who loved it and would recite line after line for hours by heart.  It's not that I didn't understand the humor.  I just didn't think it was funny.
Completely by accident, I was listening to the Cheeseshop skit on record.  I had an uncontrollable fit of laughter.  Amongst the funniest things I've ever heard and I at times when others might be inclined to shout "where's the beef," will often mutter "not much of a cheeseshop, is it?" or "well, it's certainly uncontaminated by XYZ."  But the reference is usually lost on the audience.
k