This is a cheat since it's not a city, but one of my favourite place names is Charing Cross in London.

Apparently when Queen Eleanor died somewhere up north (help! my English history is very sketchy) she was carried in state all the way to London with memorial crosses erected at all the places where the cortege stopped. The final one was at Charing Cross so named because of the beautiful stone cross erected in memory of the "Chere Reine", the Dear Queen.

I just love the way the English have mangled French expressions over time. And then they wonder why the "Frogs" despise them.