And it gets up my nose.

Bodily imagery I can understand. On my nerves - up my nose - on my tits.

Fractious animal imagery I can understand, though at some remove. It gets on my goat, it gets my gander up??

But the quince, that hedonic fruit, is the most inoffensive possible bearer of this meaning, and I find it quite puzzling. I got this from my parents, one or both of whom say it, and some of their more peculiar expressions turn out to be atavistic Scottish or North Country relics. But I can't say for sure I've ever heard the 'quince' one outside my family.