Another variant, a more recent coining with similar sentiments, and made in a working environment (I know, I was there) where technical and scientific people made their living, but were about to be made redundant, was "The Only Constant in Life is Change".

This will have particular resonance for anyone trained in mathematical or scientific disciplines, where the very concept of a constant relies on it being unchanging, immutable.

Sam

"Lasciate ogne speranza, voi ch'intrate" - 'Abandon all hope, ye who enter'.
Dante (Durante degli) Alighieri, "La Divina Commedia", "Inferno", c 1308-1321