In an O.Henry story:
"Anon he would be telling you of a cold he acquired in a Chicago lake breeze and how old Escamila cured it in Buenos Ayres with a hot infusion of the chuchula weed. "

I couldn't find anything on the Internet about that word.

I came up with quite a few Google pages, Bill, but they were pages from the O'Henry short story itself, word lists (no definitions), and surname lists. Wonder whether he either created the name or miscopied it?